![]() In visual evoked potentials, there was a normal evoked complex on the left eye and minor decrease in amplitude on the right eye. On the ocular coherence tomography, the retinal nerve fibres layer was normal. The neurological examination revealed no pathological findings. The follow-up examination 5 months later revealed no damage of basal ganglia and cerebellum on magnetic resonance imaging. Serum lactate decreased to 0.6 mmol/L the same day, and arterial blood gases became normal (pH 7.49 HCO 3 27.2 mmol/L, base excess 2.2 mmol/L, saturation O 2 0.994). No complications and adverse reactions were registered. The infusion was followed by continuous intravenous administration of 1 mL/hr/kg of 10% sodium thiosulfate at a total dose of 12 g. Hydroxocobalamin was administered 1.5 hr after ingestion in two subsequent intravenous infusions at a total dose of 7.5 g. ![]() On admission to the ICU, the patient was acidotic (pH 7.28 HCO 3 14.0 mmol/L, base excess −12.7 mmol/L, saturation O 2 0.999) with high serum lactate (12.5 mmol/L). ![]() after ingestion with the episode of generalized seizures. ![]() A 58-year-old male committed a suicide attempt by ingesting of 1200–1500 mg of potassium cyanide he was unconscious for 1–1.5 min. Hydroxocobalamin is an effective first-line antidote used mainly in monotherapy of cyanide poisonings, while the opinions are different on the effects of its combination with sodium thiosulfate. ![]()
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